Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.41 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401914 | 0.88 | LIPG (0.49) | LIPGNR1H2NR1H3SPHK1 | |
| SCHEMBL7532688 | 0.84 | KDM4E (0.49) | LIPG | |
| SCHEMBL2675807 | 0.76 | CYP3A4 (0.43) | CYP3A4NSD2POLBKCNH2SSTR1 | |
| SCHEMBL24260215 | 0.75 | CYP3A4 (0.46) | CYP3A4ALDH1A1NSD2POLBSSTR1 | |
| SCHEMBL24260305 | 0.75 | CYP3A4 (0.43) | CYP3A4ALDH1A1NSD2POLBSSTR1 | |
| SCHEMBL14785526 | 0.73 | LIPG (0.56) | LIPGNR1H2NR1H3KCNH2 | |
| SCHEMBL1567827 | 0.73 | LIPG (0.56) | LIPGNR1H2NR1H3KCNH2 | |
| SCHEMBL9418574 | 0.73 | LIPG (0.56) | LIPGNR1H2NR1H3KCNH2 | |
| SCHEMBL31139998 | 0.73 | LIPG (0.56) | LIPGNR1H2NR1H3KCNH2 | |
| SCHEMBL29785474 | 0.73 | LIPG (0.56) | LIPGNR1H2NR1H3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393761-A | Treatment of nervous system disorders | H. LUNDBECK A/S (DK) | 1995-02-28 | — | — | US | disclosed |
| EP-0470039-B1 | Novel 3-arylindole and 3-arylindazole derivatives | LUNDBECK & CO AS H (DK) | 1994-12-07 | — | — | EP | disclosed |
| EP-0470039-A2 | Novel 3-arylindole and 3-arylindazole derivatives | H. LUNDBECK A/S (DK) | 1992-02-05 | — | — | EP | disclosed |