Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24260549 | 0.88 | KMT2A (0.42) | ALDH1A1KMT2A | |
| SCHEMBL24260213 | 0.86 | CYP3A4 (0.44) | CYP3A4NSD2SSTR4SSTR1NOS2 | |
| SCHEMBL24260305 | 0.85 | CYP3A4 (0.43) | CYP3A4NSD2SSTR4SSTR1NOS2 | |
| SCHEMBL2675807 | 0.79 | CYP3A4 (0.43) | CYP3A4NSD2SSTR4SSTR1POLB | |
| SCHEMBL22605778 | 0.78 | ALDH1A1 (0.45) | CYP3A4NSD2ALDH1A1P2RX4POLB | |
| SCHEMBL10371031 | 0.78 | CDK1 (0.43) | CYP3A4NSD2SSTR4P2RX4POLB | |
| SCHEMBL3642902 | 0.75 | GAA (0.50) | CYP3A4NSD2SSTR4ALDH1A1P2RX4 | |
| SCHEMBL9280712 | 0.75 | CYP3A4 (0.46) | CYP3A4NSD2SSTR4SSTR1ALDH1A1 | |
| SCHEMBL24260258 | 0.75 | KDM4E (0.49) | SSTR4SSTR1KMT2ACHRM3 | |
| SCHEMBL22605677 | 0.74 | JAK2 (0.50) | CYP3A4NSD2ALDH1A1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11820727-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | CENTREXION THERAPEUTICS CORPORATION (US) | 2023-11-21 | — | — | US | disclosed |
| US-11254659-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | CENTREXION THERAPEUTICS CORPORATION (US) | 2022-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820727-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | TRPV1, TRPV2, TRPV3 | CYP3A4 857/4885NSD2 4038/4885SSTR4 1067/4885 |
| US-11254659-B1 | Capsaicinoid prodrug compounds and their use in treating medical conditions | TRPV1, TRPA1, TRPV2 | CYP3A4 2325/4885NSD2 4236/4885SSTR4 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.