Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9275011 | 0.89 | ALDH1A1 (0.36) | HRH3CHRM2CHRM3ALDH1A1KDM4E | |
| SCHEMBL9275071 | 0.88 | HRH3 (0.41) | HRH3CHRM2CHRM3NPSR1L3MBTL1 | |
| SCHEMBL9104408 | 0.87 | HRH3 (0.43) | HRH3CHRM2CHRM3ALDH1A1KDM4E | |
| SCHEMBL9104412 | 0.87 | HRH3 (0.43) | HRH3CHRM2CHRM3ALDH1A1KDM4E | |
| SCHEMBL9105109 | 0.85 | HRH3 (0.41) | HRH3CHRM2CHRM3ALDH1A1KDM4E | |
| SCHEMBL9102479 | 0.85 | HRH3 (0.41) | HRH3CHRM2CHRM3ALDH1A1KDM4E | |
| SCHEMBL9277892 | 0.85 | ALDH1A1 (0.43) | HRH3CHRM2CHRM3ALDH1A1KDM4E | |
| SCHEMBL9100829 | 0.82 | HRH3 (0.39) | HRH3CHRM2CHRM3ALDH1A1KDM4E | |
| SCHEMBL9100836 | 0.82 | HRH3 (0.39) | HRH3CHRM2CHRM3ALDH1A1KDM4E | |
| SCHEMBL9280247 | 0.81 | OPRD1 (0.36) | CHRM2CHRM3ALDH1A1KDM4EALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |