SCHEMBL9282200

SCHEMBL9282200

O=C(OC1=Cc2cccc3cccc(c23)C1OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.38
MAPT P10636 5/20 0.38
MEN1 O00255 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
PPARG P37231 1/20 0.38
LMNA P02545 2/20 0.36
METAP2 P50579 1/20 0.36
METAP1 P53582 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
KDM4E B2RXH2 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
TOP1 P11387 1/20 0.34
GAA P10253 2/20 0.33
JAK2 O60674 1/20 0.33
USP2 O75604 1/20 0.33
ESR1 P03372 1/20 0.33
ALOX15 P16050 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ESR2 Q92731 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6534139 0.76 ESR1 (0.37) KMT2AMAPTMEN1PPARGLMNA
SCHEMBL6533674 0.73 ESR1 (0.37) KMT2AMAPTMEN1TDP1PPARG
SCHEMBL7404645 0.70 KMT2A (0.39) KMT2AMAPTMEN1TDP1LMNA
SCHEMBL16131322 0.70 F2 (0.45) KMT2AMEN1TDP1LMNAGAA
SCHEMBL2850467 0.69 EPHX1 (0.37) KMT2AMAPTMEN1TDP1PPARG
SCHEMBL27585524 0.69 MAPT (0.45) KMT2AMAPTMEN1TDP1PPARG
SCHEMBL6533677 0.69 PPARG (0.39) KMT2AMAPTMEN1TDP1PPARG
SCHEMBL6534142 0.68 PPARG (0.38) KMT2AMAPTMEN1TDP1PPARG
SCHEMBL21778844 0.67 F2 (0.50) KMT2AMAPTMEN1TDP1LMNA
SCHEMBL12355077 0.66 KMT2A (0.61) KMT2AMAPTMEN1TDP1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7270802-A None JP disclosed
JP-H07270802-A ORIENTED FILM FOR LIQUID CRYSTAL DISPLAY ELEMENT HITACHI LTD 1995-10-20 JP disclosed