Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534139 | 0.82 | ESR1 (0.37) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL253445 | 0.77 | THRB (0.38) | MAPTALDH1A1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL28979493 | 0.76 | HTT (0.39) | MAPTALDH1A1POLBNPC1GAA | |
| SCHEMBL6533677 | 0.76 | PPARG (0.39) | ESR1ESR2MAPTKMT2AMEN1 | |
| SCHEMBL21859029 | 0.75 | TSHR (0.31) | ALDH1A1TSHR | |
| SCHEMBL9282200 | 0.73 | KMT2A (0.38) | ESR1ESR2MAPTKMT2AMEN1 | |
| SCHEMBL16131318 | 0.71 | LMNA (0.42) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL6046323 | 0.70 | KMT2A (0.31) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL21758200 | 0.69 | LMNA (0.46) | ESR1CA12CA1CA2CA7 | |
| SCHEMBL27335888 | 0.68 | PPARG (0.36) | CA12CA9MAPTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572716-A2 | METHODS FOR SYNTHESIS OF LIQUID CRYSTALS | Southwest Research Institute (US) | 2005-09-14 | — | — | EP | disclosed |
| EP-1572716-A4 | METHODS FOR SYNTHESIS OF LIQUID CRYSTALS | SOUTHWEST RES INST (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2002066493-A2 | METHODS FOR SYNTHESIS OF LIQUID CRYSTALS | SOUTHWEST RESEARCH INSTITUTE (US) | 2002-08-29 | — | — | WO | disclosed |