Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28991134 | 0.75 | CYP1A2 (0.46) | CYP3A4CYP2C9CYP2C19NPSR1CYP1A2 | |
| SCHEMBL9282288 | 0.73 | CYP3A4 (0.33) | KIF11CYP3A4CYP2C9CYP2C19NPSR1 | |
| SCHEMBL5689660 | 0.69 | CYP1A2 (0.37) | NPSR1CYP1A2CYP2D6 | |
| SCHEMBL9489530 | 0.68 | KIF11 (0.39) | KIF11CYP2C19CYP1A2CYP2D6PTPN1 | |
| SCHEMBL27803061 | 0.68 | MDM4 (0.38) | KMT2A | |
| SCHEMBL6037245 | 0.68 | CYP1A2 (0.42) | KIF11CYP3A4CYP2C9CYP2C19NPSR1 | |
| SCHEMBL6037246 | 0.68 | CYP1A2 (0.42) | KIF11CYP3A4CYP2C9CYP2C19NPSR1 | |
| SCHEMBL8064248 | 0.67 | NPSR1 (0.37) | KIF11CYP3A4CYP2C9CYP2C19NPSR1 | |
| SCHEMBL3810303 | 0.65 | CYP1A2 (0.37) | KIF11CYP3A4CYP2C9CYP2C19NPSR1 | |
| SCHEMBL3810305 | 0.65 | CYP1A2 (0.37) | KIF11CYP3A4CYP2C9CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391808-A | Lubricant and synthetic polymer additives for heat and oxidation resistance | CIBA-GEIGY CORPORATION (US) | 1995-02-21 | — | — | US | disclosed |