Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3810303 | 0.84 | CYP1A2 (0.37) | NPSR1ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL3810305 | 0.84 | CYP1A2 (0.37) | NPSR1ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL7165975 | 0.77 | SMN1; SMN2 (0.46) | NPSR1ALDH1A1CYP2C19CYP3A4CYP2C9 | |
| SCHEMBL28263787 | 0.69 | KMT2A (0.38) | NPSR1ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL6285599 | 0.68 | KMT2A (0.44) | NPSR1ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL674052 | 0.68 | KMT2A (0.44) | NPSR1ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL8607670 | 0.68 | ALDH1A1 (0.51) | ALDH1A1KMT2ACYP2C19TSHRCYP3A4 | |
| SCHEMBL8607678 | 0.68 | ALDH1A1 (0.51) | ALDH1A1KMT2ACYP2C19TSHRCYP3A4 | |
| SCHEMBL9282285 | 0.67 | KIF11 (0.33) | NPSR1ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL2090336 | 0.67 | CYP1A2 (0.45) | ALDH1A1KMT2ACYP2C19HIF1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643778-B1 | ENCODED COMBINATORIAL CHEMICAL LIBRARIES | SCRIPPS RESEARCH INST (US) | 2000-05-31 | — | — | EP | disclosed |
| US-6060596-A | BIFUNCTIONAL MOLECULES HAVING BOTH A CHEMICAL POLYMER AND AN IDENTIFIER OLIGONUCLEOTIDE SEQUENCE THAT DEFINES THE STRUCTURE OF THE CHEMICAL POLYMER. | THE SCRIPPS RESEARCH INSTITUTE (US) | 2000-05-09 | — | — | US | disclosed |
| US-5723598-A | Encoded combinatorial chemical libraries | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-03-03 | — | — | US | disclosed |
| EP-0575273-B1 | Crosslinkable derivatives of collagen, process for obtaining the same and their use in the preparation of biomaterials | FLAMEL TECH SA (FR) | 1997-12-03 | — | — | EP | disclosed |
| US-5573905-A | Encoded combinatorial chemical libraries | THE SCRIPPS RESEARCH INSTITUTE (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0643778-A4 | ENCODED COMBINATORIAL CHEMICAL LIBRARIES. | SCRIPPS RESEARCH INST (US) | 1995-09-20 | — | — | EP | disclosed |
| EP-0643778-A1 | ENCODED COMBINATORIAL CHEMICAL LIBRARIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-03-22 | — | — | EP | disclosed |
| EP-0575273-A1 | Crosslinkable derivatives of collagen, process for obtaining the same and their use in the preparation of biomaterials | FLAMEL TECHNOLOGIES, Société Anonyme (FR) | 1993-12-22 | — | — | EP | disclosed |
| WO-1993020242-A1 | ENCODED COMBINATORIAL CHEMICAL LIBRARIES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1993-10-14 | — | — | WO | disclosed |