Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 15/20 | 0.65 |
| ▸ | NOS1 | P29475 | 11/20 | 0.65 |
| ▸ | NOS3 | P29474 | 9/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7052362 | 0.79 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL30967285 | 0.76 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL13040574 | 0.76 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL13040572 | 0.76 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL13040600 | 0.73 | NOS2 (0.69) | NOS2NOS1NOS3 | |
| SCHEMBL7048505 | 0.71 | NOS2 (0.77) | NOS2NOS1NOS3 | |
| SCHEMBL7049660 | 0.71 | NOS2 (0.77) | NOS2NOS1NOS3 | |
| SCHEMBL7048509 | 0.71 | NOS2 (0.77) | NOS2NOS1NOS3 | |
| SCHEMBL13040654 | 0.71 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL7051205 | 0.69 | NOS2 (1.00) | NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996018616-A1 | SUBSTITUTED 2-AMINOPYRIDINES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |