Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 13/20 | 1.00 |
| ▸ | NOS1 | P29475 | 8/20 | 1.00 |
| ▸ | NOS3 | P29474 | 7/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL160399 | 0.85 | NOS2 (0.73) | NOS2NOS1NOS3 | |
| SCHEMBL30967285 | 0.85 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL13040572 | 0.85 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL13040574 | 0.85 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL13040600 | 0.82 | NOS2 (0.69) | NOS2NOS1NOS3 | |
| SCHEMBL7051205 | 0.81 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL12250722 | 0.79 | NOS2 (0.66) | NOS2NOS1NOS3 | |
| SCHEMBL9282575 | 0.79 | NOS2 (0.65) | NOS2NOS1NOS3 | |
| SCHEMBL13040654 | 0.79 | NOS2 (1.00) | NOS2NOS1NOS3 | |
| SCHEMBL12250784 | 0.78 | NOS2 (0.63) | NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003013523-A1 | SH3 PROTEIN DOMAINS AND THEIR LIGANDS | ADELAIDE RESEARCH & INNOVATION PTY LTD (AU) | 2003-02-20 | — | — | WO | claimed |
| US-5972975-A | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase | MERCK & CO., INC. (US) | 1999-10-26 | — | — | US | claimed |
| US-20100278751-A1 | RADIOLABELED 2-AMINO-4-ALKYL-6-(HALOALKYL)PYRIDINE COMPOUNDS AND THEIR USE IN DIAGNOSTIC IMAGING | WASHINGTON UNIVERSITY (US) | 2010-11-04 | — | — | US | disclosed |
| US-20100278751-A1 | RADIOLABELED 2-AMINO-4-ALKYL-6-(HALOALKYL)PYRIDINE COMPOUNDS AND THEIR USE IN DIAGNOSTIC IMAGING | WASHINGTON UNIVERSITY (US) | 2010-11-04 | — | — | US | disclosed |
| WO-2003013523-A1 | SH3 PROTEIN DOMAINS AND THEIR LIGANDS | ADELAIDE RESEARCH & INNOVATION PTY LTD (AU) | 2003-02-20 | — | — | WO | disclosed |
| US-5972975-A | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase | MERCK & CO., INC. (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1996018616-A1 | SUBSTITUTED 2-AMINOPYRIDINES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100278751-A1 | RADIOLABELED 2-AMINO-4-ALKYL-6-(HALOALKYL)PYRIDINE COMPOUNDS AND THEIR USE IN DIAGNOSTIC IMAGING | NOS2, NOS3, NOS1 | NOS2 1/4885NOS1 3/4885NOS3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.