SCHEMBL928289

SCHEMBL928289

Oc1ccc(-c2ccccc2)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 5/20 1.00
APP P05067 3/20 0.76
KDM4E B2RXH2 1/20 0.64
MEN1 O00255 1/20 0.64
USP2 O75604 1/20 0.64
ALDH1A1 P00352 1/20 0.64
LMNA P02545 1/20 0.64
HSP90AA1 P07900 1/20 0.64
GAA P10253 1/20 0.64
MAPT P10636 1/20 0.64
HPGD P15428 1/20 0.64
ALOX15 P16050 1/20 0.64
ALOX12 P18054 1/20 0.64
HTT P42858 1/20 0.64
KMT2A Q03164 1/20 0.64
HSD17B10 Q99714 1/20 0.64
ESR2 Q92731 1/20 0.64
QDPR P09417 3/20 0.60
ACMSD Q8TDX5 3/20 0.59
HNF4A P41235 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29848221 1.00 ALOX5 (1.00) ALOX5APPKDM4EMEN1USP2
Methane SCHEMBL28271157 0.97 ALOX5 (0.95) ALOX5APPKDM4EMEN1USP2
SCHEMBL27714322 0.97 ALOX5 (0.95) ALOX5APPKDM4EMEN1USP2
SCHEMBL28134269 0.95 ALOX5 (0.91) ALOX5APPKDM4EMEN1USP2
Formaldehyde SCHEMBL28374238 0.93 ALOX5 (0.86) ALOX5APPKDM4EMEN1USP2
Bicarbonate SCHEMBL11789771 0.93 ALOX5 (0.86) ALOX5APPKDM4EMEN1USP2
SCHEMBL30016853 0.92 APP (0.90) ALOX5APPKDM4EMEN1USP2
Sulfur Dioxide SCHEMBL22500872 0.91 ALOX5 (0.83) ALOX5APPKDM4EMEN1USP2
SCHEMBL27880220 0.91 ALOX5 (0.83) ALOX5APPKDM4EMEN1USP2
SCHEMBL28053825 0.91 ALOX5 (0.83) ALOX5APPKDM4EMEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 650 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250276107-A1 HYDROGEL SYSTEMS AND METHODS FOR TREATING FISTULA AND OTHER INDICATIONS TERASAKI INSTITUTE FOR BIOMEDICAL INNOVATION (US) 2025-09-04 US claimed
CN-113264895-B Synthetic method for preparing benzoxazole compound from catechol compound and amine compound 湖南第一师范学院 2022-03-25 CN claimed
CN-114144454-A Improved operating time to open-run time ratio by adding phenolic catalysts to polyaspartic flooring formulations 科思创有限公司 2022-03-04 CN claimed
CN-113264895-A Synthetic method for preparing benzoxazole compound from catechol compound and amine compound 湖南第一师范学院 2021-08-17 CN claimed
CN-101068773-A Melanin concentrating hormone antagonists PROCTER & GAMBLE (US) 2007-11-07 CN claimed
EP-1667958-A2 MELANIN CONCENTRATING HORMONE ANTAGONISTS THE PROCTER & GAMBLE COMPANY (US) 2006-06-14 EP claimed
WO-2005033063-A2 MELANIN CONCENTRATING HORMONE ANTAGONISTS THE PROCTER & GAMBLE COMPANY (US) 2005-04-14 WO claimed
US-20050075324-A1 Melanin concentrating hormone antagonists THE PROCTER & GAMBLE COMPANY (US) 2005-04-07 US claimed
US-6280923-B1 LIGHT-INSENSITIVE SILVER SALT OF AN ORGANIC CARBOXYLIC ACID; PHOTOSENSITIVE SILVER HALIDE; BINDER; ORGANIC REDUCING AGENT FOR SAID SUBSTANTIALLY LIGHT-INSENSITIVE SILVER SALT AGFA-GEVAERT (BE) 2001-08-28 US claimed
WO-1995000129-A1 TREATMENT OF MULTIDRUG RESISTANT DISEASES CHEMEX PHARMACEUTICALS INC. (US) 1995-01-05 WO claimed
EP-0213454-B1 HEAT SENSITIVE RECORDING SHEETS CONTAINING SULFONE DERIVATIVES KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-12-02 EP claimed
US-4725533-A SILVER HALIDE LAYER AND TANNING DEVELOPER DISPERSED IN HIGH BOILING SOLVENT IN SEPARATE LAYER FUJI PHOTO FILM CO., LTD. (JP) 1988-02-16 US claimed
US-4283478-A COMPRISING A SILVER HALIDE LAYER AND A LAYER OF POSITIVE WORKING LIGHT SENSITIVE RESIN FUJI PHOTO FILM CO., LTD. (JP) 1981-08-11 US claimed
US-4221858-A EXPOSURE, SILVER HALIDE EMULSIONS, TANNING FUJI PHOTO FILM CO., LTD. (JP) 1980-09-09 US claimed
US-4196112-A ADDUCT OF A BUTADIENE POLYMER AN A,B-ACID, A CARBOCYCLIC ALCOHOL GELATION INHIBITOR, A HYDROPHILIC SOLVENT, A NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1980-04-01 US claimed
US-4175068-A ADDUCT OF BUTADIENE AND UNSATURATED DICARBOXYLIC ACID, NEUTRALIZER NIPPON OIL CO., LTD. (JP) 1979-11-20 US claimed
US-4173477-A SILVER HALIDE; ALUMINUM SUPPORT, ANODIZED ALUMINUM OXIDE LAYER, 4-PHENYLCATECHOL; LITHOGRAPHIC PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1979-11-06 US claimed
US-3970458-A PHOTOGRAPHY EASTMAN KODAK COMPANY (US) 1976-07-20 US claimed
US-3970459-A Process for developing a direct reversal silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed
US-3965033-A Process for the production of oil-containing microcapsules FUJI PHOTO FILM CO., LTD. (JA) 1976-06-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050075324-A1 Melanin concentrating hormone antagonists MCHR1, MCHR2, MC1R ALOX5 1381/4885APP 4164/4885KDM4E 3266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.