Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032811 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2RAB9AMAPK1MAPTHCRTR1 | |
| SCHEMBL5032877 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2RAB9AMAPK1MAPTHCRTR1 | |
| SCHEMBL9284413 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9AMAPK1MAPTHCRTR1 | |
| Bromide SCHEMBL5036774 | 0.83 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9AMAPK1MAPTHCRTR1 | |
| SCHEMBL9283229 | 0.75 | ALDH1A1 (0.44) | SMN1; SMN2RAB9AMAPK1MAPTHCRTR1 | |
| SCHEMBL5035217 | 0.70 | ALDH1A1 (0.38) | SMN1; SMN2RAB9AMAPK1MAPTHCRTR1 | |
| SCHEMBL5035286 | 0.68 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9AMAPK1MAPTHCRTR1 | |
| SCHEMBL7502575 | 0.68 | SMN1; SMN2 (0.78) | SMN1; SMN2RAB9AMAPK1MAPTHCRTR1 | |
| SCHEMBL20579804 | 0.68 | SMN1; SMN2 (0.78) | SMN1; SMN2RAB9AMAPK1MAPTHCRTR1 | |
| SCHEMBL7499292 | 0.67 | SMN1; SMN2 (0.76) | SMN1; SMN2RAB9AMAPK1MAPTHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995027714-A1 | ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1995-10-19 | — | — | WO | disclosed |