Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 2/20 | 0.37 |
| ▸ | ATP4B | P51164 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032811 | 0.84 | SMN1; SMN2 (0.57) | ALDH1A1RAB9AHPGDSMN1; SMN2CYP1A2 | |
| Hydrochloric Acid SCHEMBL11050041 | 0.83 | ATP4A (0.50) | ALDH1A1HSD11B1ATP4AATP4BRAB9A | |
| SCHEMBL5327618 | 0.78 | GLA (0.38) | ALDH1A1HSD11B1GLARAB9AHPGD | |
| Bicarbonate SCHEMBL5984921 | 0.77 | GLA (0.37) | ALDH1A1HSD11B1GLARAB9AHPGD | |
| SCHEMBL5322465 | 0.77 | GLA (0.35) | ALDH1A1HSD11B1GLARAB9AGSK3B | |
| SCHEMBL5329533 | 0.74 | CYP3A4 (0.36) | ALDH1A1HSD11B1GLARAB9AHPGD | |
| SCHEMBL4994479 | 0.74 | KMT2A (0.36) | ALDH1A1HSD11B1GLARAB9AHPGD | |
| Bicarbonate SCHEMBL4976269 | 0.74 | KMT2A (0.35) | ALDH1A1HSD11B1GLARAB9AHPGD | |
| SCHEMBL5330704 | 0.74 | SMN1; SMN2 (0.43) | ALDH1A1RAB9AHPGDSMN1; SMN2CYP1A2 | |
| SCHEMBL5327607 | 0.72 | HSD11B1 (0.35) | ALDH1A1HSD11B1GLARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984969-B1 | FUSED DIHYDROPYRANS | NYCOMED GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |
| US-6160119-A | Fused dihydropyrans | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-12-12 | — | — | US | disclosed |
| EP-0984969-A1 | FUSED DIHYDROPYRANS | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054188-A1 | FUSED DIHYDROPYRANS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-12-03 | — | — | WO | disclosed |