Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GPER1 | Q99527 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527586 | 0.82 | ALOX5 (0.72) | ALOX5EPHX2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9285681 | 0.78 | ALOX5 (0.46) | ALOX5EPHX2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9285478 | 0.78 | ALOX5 (0.46) | ALOX5EPHX2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9025191 | 0.77 | ALOX5 (0.58) | ALOX5EPHX2SMN1; SMN2 | |
| SCHEMBL9025062 | 0.75 | ALOX5 (0.56) | ALOX5EPHX2ALDH1A1GAA | |
| SCHEMBL9025000 | 0.75 | ALOX5 (0.56) | ALOX5EPHX2 | |
| SCHEMBL9025772 | 0.75 | ALOX5 (0.55) | ALOX5EPHX2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8309551 | 0.74 | ALOX5 (1.00) | ALOX5EPHX2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8305231 | 0.74 | ALOX5 (0.58) | ALOX5EPHX2SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9025522 | 0.73 | ALOX5 (0.53) | ALOX5EPHX2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995030671-A1 | SUBSTITUTED ARYL- AND HETEROARYLALKENYL-N-HYDROXYUREA INHIBITORS OF LEUKOTRIENE BIOSYNTHESIS | ABBOTT LABORATORIES (US) | 1995-11-16 | — | — | WO | disclosed |