Phenol

Phenol

SCHEMBL9283158

C=CCSC[S+]([O-])CSCC=C.Oc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
GLA P06280 1/20 0.38
CA3 P07451 1/20 0.38
CA4 P22748 1/20 0.38
CA9 Q16790 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CA14 Q9ULX7 1/20 0.38
ESR1 P03372 2/20 0.35
ALOX5 P09917 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
ESR2 Q92731 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diallyl Sulfide SCHEMBL1449847 0.83 CA12 (0.50) CA12CA1CA2GLACA3
Diallyl Sulfide SCHEMBL11645334 0.83 CA12 (0.50) CA12CA1CA2GLACA3
Diallyl Sulfide SCHEMBL7949631 0.81 CA12 (0.48) CA12CA1CA2GLACA3
Diallyl Sulfide SCHEMBL1979798 0.81 CA12 (0.48) CA12CA1CA2GLACA3
Diallyldisulfide SCHEMBL28956854 0.75 ALDH1A1 (0.50) CA12CA1CA2GLACA3
Diallyldisulfide SCHEMBL668587 0.75 ALDH1A1 (0.50) CA12CA1CA2GLACA3
Diallyl Sulfide SCHEMBL27472402 0.75 ACHE (0.41) CA12CA1CA2GLACA3
Allicin SCHEMBL28241139 0.75 CA12 (0.37) CA12CA1CA2GLACA3
Resorcinol SCHEMBL27991338 0.70 CA12 (0.52) CA12CA1CA2CA9TDP1
Phenol SCHEMBL11597390 0.68 CA12 (0.58) CA12CA1CA2GLACA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0473549-B1 Sulfoxides of alkylthiomethylphenols CIBA GEIGY AG (CH) 1995-01-25 EP disclosed
EP-0473549-A1 Sulfoxides of alkylthiomethylphenols CIBA-GEIGY AG (CH) 1992-03-04 EP disclosed