Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 7/20 | 0.39 |
| ▸ | HTR2B | P41595 | 6/20 | 0.39 |
| ▸ | HTR2A | P28223 | 4/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9283243 | 1.00 | TP53 (0.53) | TP53MDM2MEN1KMT2APOLB | |
| SCHEMBL9283247 | 1.00 | TP53 (0.53) | TP53MDM2MEN1KMT2APOLB | |
| SCHEMBL9309239 | 0.84 | TP53 (0.53) | TP53MDM2MEN1KMT2APOLB | |
| SCHEMBL9309243 | 0.84 | TP53 (0.53) | TP53MDM2MEN1KMT2APOLB | |
| SCHEMBL9309234 | 0.84 | TP53 (0.53) | TP53MDM2MEN1KMT2APOLB | |
| SCHEMBL11477337 | 0.79 | CHRM2 (0.57) | TP53MDM2MEN1KMT2APOLB | |
| SCHEMBL21104990 | 0.69 | KMT2A (0.51) | TP53MDM2MEN1KMT2APOLB | |
| SCHEMBL19750826 | 0.68 | SIGMAR1 (0.45) | TP53MDM2MEN1KMT2APOLB | |
| SCHEMBL21056614 | 0.66 | KMT2A (0.76) | MEN1KMT2APOLBSRD5A1HTT | |
| SCHEMBL25017953 | 0.66 | CHRM2 (0.57) | MEN1KMT2APOLBCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995023135-A1 | DIPHENYL-2-PIPERIDINONE AND -2-PYRROLIDINONE DERIVATIVES HAVING ANTI-CONVULSANT AND NEUROPROTECTIVE ACTIVITY | FISONS CORPORATION (US) | 1995-08-31 | — | — | WO | claimed |
| US-5334720-A | Diphenyl-1-(aminoalkyl)-2-piperidinone and -2-pyrrolidinone derivatives having anticonvulsant properties | FISONS CORPORATION (US) | 1994-08-02 | — | — | US | disclosed |