Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 9/20 | 0.53 |
| ▸ | MDM2 | Q00987 | 9/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9309243 | 1.00 | TP53 (0.53) | TP53MDM2KMT2AMEN1POLB | |
| SCHEMBL9309234 | 1.00 | TP53 (0.53) | TP53MDM2KMT2AMEN1POLB | |
| SCHEMBL9283240 | 0.84 | TP53 (0.53) | TP53MDM2KMT2AMEN1POLB | |
| SCHEMBL9283243 | 0.84 | TP53 (0.53) | TP53MDM2KMT2AMEN1POLB | |
| SCHEMBL9283247 | 0.84 | TP53 (0.53) | TP53MDM2KMT2AMEN1POLB | |
| SCHEMBL24508712 | 0.70 | CHRM2 (0.55) | KMT2AMEN1POLBCHRM2CHRM4 | |
| SCHEMBL21104990 | 0.69 | KMT2A (0.51) | TP53MDM2KMT2AMEN1POLB | |
| SCHEMBL21056614 | 0.69 | KMT2A (0.76) | KMT2AMEN1POLBHTTSRD5A1 | |
| SCHEMBL19750826 | 0.68 | SIGMAR1 (0.45) | TP53MDM2KMT2AMEN1POLB | |
| SCHEMBL10687774 | 0.68 | KMT2A (0.67) | TP53MDM2KMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334720-A | Diphenyl-1-(aminoalkyl)-2-piperidinone and -2-pyrrolidinone derivatives having anticonvulsant properties | FISONS CORPORATION (US) | 1994-08-02 | — | — | US | disclosed |