Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | LYN | P07948 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyprodinil SCHEMBL29421756 | 0.93 | TAAR1 (0.55) | TAAR1SMN1; SMN2HTTIGF1RMAPT | |
| Cyprodinil SCHEMBL22669 | 0.93 | TAAR1 (0.55) | TAAR1SMN1; SMN2HTTIGF1RMAPT | |
| Cyprodinil SCHEMBL12471945 | 0.92 | SMN1; SMN2 (0.54) | TAAR1SMN1; SMN2HTTIGF1RMAPT | |
| Pyrimethanil SCHEMBL1467035 | 0.84 | SMN1; SMN2 (0.61) | TAAR1SMN1; SMN2HTTKCNH2CDK2 | |
| Cyprodinil SCHEMBL2553905 | 0.83 | TAAR1 (0.46) | TAAR1SMN1; SMN2HTTIGF1RMAPT | |
| Cyprodinil SCHEMBL15153945 | 0.83 | TAAR1 (0.46) | TAAR1SMN1; SMN2HTTIGF1RMAPT | |
| SCHEMBL9499662 | 0.82 | ALDH1A1 (0.49) | TAAR1SMN1; SMN2HTTNEK1MAPT | |
| SCHEMBL8895354 | 0.82 | TAAR1 (0.40) | TAAR1HTTIGF1RCDK2MARK3 | |
| Cyprodinil SCHEMBL8346330 | 0.82 | TAAR1 (0.45) | TAAR1SMN1; SMN2HTTIGF1RMAPT | |
| Mepanipyrim SCHEMBL18132072 | 0.81 | TAAR1 (0.44) | TAAR1SMN1; SMN2HTTIGF1RCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7017811-A | — | — | None | — | — | JP | disclosed |
| JP-H0717811-A | MICROBICIDE | CIBA GEIGY AG | 1995-01-20 | — | — | JP | disclosed |
| JP-H00717811-A | — | — | 0001-01-01 | — | — | JP | disclosed |