Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 4/20 | 0.63 |
| ▸ | RAB9A | P51151 | 4/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | POLB | P06746 | 6/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.59 |
| ▸ | CASP7 | P55210 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | METAP1 | P53582 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45506 | 0.87 | MAPT (0.68) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL4309362 | 0.85 | MAPT (0.71) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL8871046 | 0.85 | MAPT (0.67) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL8871380 | 0.81 | SMN1; SMN2 (0.65) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL28678208 | 0.81 | MAPT (1.00) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL8886917 | 0.81 | MAPT (0.61) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL15818384 | 0.80 | MAPT (0.60) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9284194 | 0.80 | MAPT (0.60) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9343462 | 0.79 | MAPT (0.59) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL8624763 | 0.79 | MAPT (0.59) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0407341-B1 | Selective herbicidal agent | CIBA GEIGY AG (CH) | 1995-12-06 | — | — | EP | claimed |