Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.63 |
| ▸ | HPGD | P15428 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | OGG1 | O15527 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309362 | 0.83 | MAPT (0.71) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL8628518 | 0.82 | SMN1; SMN2 (1.00) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9284192 | 0.81 | MAPT (0.68) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL45506 | 0.81 | MAPT (0.68) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL8871046 | 0.80 | MAPT (0.67) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL4639142 | 0.80 | SCN9A (0.70) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL9871210 | 0.80 | RAB9A (0.69) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL15517101 | 0.79 | MAPT (0.65) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL15516810 | 0.79 | MAPT (0.65) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 | |
| SCHEMBL28131091 | 0.79 | HSP90AA1 (0.68) | MAPTSMN1; SMN2NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120317-B | Biquinoline functionalized naphthalimide derivative, preparation thereof and application thereof in detection and separation of hydrazine hydrate | 西北民族大学 | 2025-03-25 | — | — | CN | claimed |
| CN-116120317-A | Biquinoline functionalized naphthalimide derivative, preparation thereof and application thereof in detection and separation of hydrazine hydrate | 西北民族大学 | 2023-05-16 | — | — | CN | claimed |
| CN-110156762-B | Aggregation-induced emission material containing quinoline and coumarin functional groups and preparation method thereof | 山西大学 | 2021-12-31 | — | — | CN | claimed |
| CN-116120317-B | Biquinoline functionalized naphthalimide derivative, preparation thereof and application thereof in detection and separation of hydrazine hydrate | 西北民族大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-116120317-B | Biquinoline functionalized naphthalimide derivative, preparation thereof and application thereof in detection and separation of hydrazine hydrate | 西北民族大学 | 2025-03-25 | — | — | CN | disclosed |
| CN-118406008-A | Quinoline modification-based bishydrazide functional pincer compound and synthesis and application thereof | 西北民族大学 | 2024-07-30 | — | — | CN | disclosed |
| CN-116120317-A | Biquinoline functionalized naphthalimide derivative, preparation thereof and application thereof in detection and separation of hydrazine hydrate | 西北民族大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-116120317-A | Biquinoline functionalized naphthalimide derivative, preparation thereof and application thereof in detection and separation of hydrazine hydrate | 西北民族大学 | 2023-05-16 | — | — | CN | disclosed |
| CN-110156762-B | Aggregation-induced emission material containing quinoline and coumarin functional groups and preparation method thereof | 山西大学 | 2021-12-31 | — | — | CN | disclosed |