Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 14/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 13/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183424 | 0.87 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9263765 | 0.85 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9263754 | 0.84 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8953229 | 0.82 | — | — | |
| SCHEMBL9179727 | 0.79 | AGTR1 (0.38) | AGTR1AGTR2GRIN2B | |
| SCHEMBL16824595 | 0.75 | AGTR1 (0.43) | AGTR1AGTR2HDAC1 | |
| SCHEMBL8088507 | 0.74 | JAK2 (0.35) | AGTR1AGTR2HDAC1 | |
| Hydrochloric Acid SCHEMBL21065250 | 0.73 | AGTR1 (0.35) | AGTR1AGTR2HDAC1 | |
| SCHEMBL8953335 | 0.72 | — | — | |
| SCHEMBL9264451 | 0.72 | AGTR1 (0.77) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476857-A | Imidazopyridines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-12-19 | — | — | US | disclosed |