Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.38 |
| ▸ | AGTR2 | P50052 | 8/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9183424 | 0.89 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9263765 | 0.81 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9285111 | 0.79 | AGTR1 (0.44) | AGTR1AGTR2GRIN2B | |
| SCHEMBL9263754 | 0.78 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL8953335 | 0.73 | — | — | |
| SCHEMBL9183451 | 0.72 | AGTR1 (0.36) | AGTR1AGTR2 | |
| SCHEMBL9478800 | 0.72 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9479341 | 0.68 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL9179794 | 0.68 | GRM2 (0.43) | HSD17B10GRIN2B | |
| SCHEMBL9479331 | 0.68 | AGTR1 (0.44) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5405964-A | Angiotensin antagonist | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1995-04-11 | — | — | US | disclosed |