Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.34 |
| ▸ | CA2 | P00918 | 4/20 | 0.34 |
| ▸ | CA9 | Q16790 | 4/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9281009 | 1.00 | DNM1 (0.42) | DNM1TSHRTHRBMEN1HTT | |
| Hydrochloric Acid SCHEMBL9282868 | 1.00 | DNM1 (0.42) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL6679948 | 0.95 | DNM1 (0.46) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL29034461 | 0.95 | DNM1 (0.46) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL4791083 | 0.93 | DNM1 (0.42) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL2352064 | 0.91 | DNM1 (0.42) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL6678479 | 0.91 | DNM1 (0.42) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL9766741 | 0.91 | DNM1 (0.40) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL28126402 | 0.86 | DNM1 (0.42) | DNM1TSHRTHRBMEN1HTT | |
| SCHEMBL5552916 | 0.86 | DNM1 (0.40) | DNM1TSHRTHRBMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0349886-B1 | Liquid catalyst component, catalyst system containing said component and process for producing ethylene-alpha-olefin copolymer using said catalyst system | SUMITOMO CHEMICAL CO (JP) | 1995-09-20 | — | — | EP | disclosed |
| US-5134104-A | Coordination catalyst | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-07-28 | — | — | US | disclosed |
| US-5039766-A | Coordination polymerization catalyst | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-08-13 | — | — | US | disclosed |