Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 10/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6380177 | 0.94 | MAOA (0.43) | SERPINE1MAOAMAOBKMT2AMAPT | |
| SCHEMBL6380185 | 0.94 | MAOA (0.43) | SERPINE1MAOAMAOBKMT2AMAPT | |
| SCHEMBL6374925 | 0.91 | MAOA (0.44) | SERPINE1MAOAMAOBKMT2AMAPT | |
| SCHEMBL6374936 | 0.91 | MAOA (0.44) | SERPINE1MAOAMAOBKMT2AMAPT | |
| SCHEMBL6371814 | 0.80 | SMN1; SMN2 (0.46) | SERPINE1MAOAMAOBKMT2AMAPT | |
| SCHEMBL6371821 | 0.80 | SMN1; SMN2 (0.46) | SERPINE1MAOAMAOBKMT2AMAPT | |
| SCHEMBL6376092 | 0.78 | SERPINE1 (0.56) | SERPINE1MAOAMAOBKMT2AMAPT | |
| SCHEMBL6376088 | 0.78 | SERPINE1 (0.56) | SERPINE1MAOAMAOBKMT2AMAPT | |
| SCHEMBL8596135 | 0.74 | KMT2A (0.53) | SERPINE1KMT2AMAPTMEN1POLB | |
| SCHEMBL8596133 | 0.74 | KMT2A (0.53) | SERPINE1KMT2AMAPTMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655060-A1 | PHARMACEUTICALLY ACTIVE DIKETOPIPERAZINES | XENOVA LIMITED (GB) | 1995-05-31 | — | — | EP | claimed |