Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | REN | P00797 | 15/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9285348 | 1.00 | P2RX1 (0.50) | P2RX1RENHPGDRECQLMEN1 | |
| SCHEMBL9279537 | 1.00 | P2RX1 (0.50) | P2RX1RENHPGDRECQLMEN1 | |
| SCHEMBL9279542 | 1.00 | P2RX1 (0.50) | P2RX1RENHPGDRECQLMEN1 | |
| SCHEMBL9279210 | 0.82 | REN (0.47) | P2RX1REN | |
| SCHEMBL9279217 | 0.82 | REN (0.47) | P2RX1REN | |
| SCHEMBL9285769 | 0.82 | REN (0.47) | P2RX1REN | |
| SCHEMBL9279223 | 0.82 | REN (0.47) | P2RX1REN | |
| SCHEMBL7433840 | 0.82 | P2RX1 (0.46) | P2RX1REN | |
| SCHEMBL8909057 | 0.82 | P2RX1 (0.62) | P2RX1REN | |
| SCHEMBL7277076 | 0.82 | P2RX1 (0.46) | P2RX1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |