Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28248744 | 0.80 | LMNA (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL5768011 | 0.78 | LMNA (0.44) | LMNACA12CA1CA2CA3 | |
| SCHEMBL628286 | 0.76 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL3725271 | 0.76 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| SCHEMBL169032 | 0.75 | LMNA (0.43) | LMNACA12CA1CA2CA3 | |
| SCHEMBL11353115 | 0.73 | LMNA (0.49) | LMNACA12CA1CA2CA3 | |
| Acrylic Acid SCHEMBL21798556 | 0.72 | LMNA (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL8331968 | 0.71 | LMNA (0.44) | LMNACA12CA1CA2CA3 | |
| SCHEMBL15106072 | 0.71 | LMNA (0.44) | LMNACA12CA1CA2CA3 | |
| SCHEMBL22228539 | 0.71 | LMNA (0.42) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519877-B1 | 3-Acylamino-2-pyrrolidinones as enhancers of the processes of learning and memory and pharmaceutical compositions containing same | SIGMA TAU IND FARMACEUTI (IT) | 1995-09-27 | — | — | EP | disclosed |