Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22228539 | 0.79 | LMNA (0.42) | LMNACA12CA1CA2CA3 | |
| SCHEMBL2575684 | 0.78 | LMNA (0.41) | LMNACA12CA1CA2CA3 | |
| SCHEMBL7355170 | 0.77 | LMNA (0.45) | LMNACA12CA1CA2CA3 | |
| SCHEMBL2362411 | 0.77 | — | — | |
| SCHEMBL2451756 | 0.76 | LMNA (0.43) | LMNACA12CA1CA2CA3 | |
| SCHEMBL21200450 | 0.76 | LMNA (0.40) | LMNACA12CA1CA2CA3 | |
| SCHEMBL1682218 | 0.76 | LMNA (0.43) | LMNACA12CA1CA2CA3 | |
| SCHEMBL5768011 | 0.76 | LMNA (0.44) | LMNACA12CA1CA2CA3 | |
| SCHEMBL9286162 | 0.75 | LMNA (0.41) | LMNACA12CA1CA2CA3 | |
| SCHEMBL22228550 | 0.73 | LMNA (0.37) | LMNACA12CA1CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2018 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113775-A1 | ANHYDROUS COMPOSITIONS OF EGFR INHIBITORS AND METHODS OF USE | PALVELLA THERAPEUTICS, INC. (US) | 2023-04-13 | — | — | US | claimed |
| WO-2023039470-A1 | ANHYDROUS COMPOSITIONS OF EGFR INHIBITORS AND METHODS OF USE | PALVELLA THERAPEUTICS, INC. (US) | 2023-03-16 | — | — | WO | claimed |
| CN-111978703-A | Temperature-control color-changing dimming material and application thereof | 南京施瓦乐新材料科技有限公司 | 2020-11-24 | — | — | CN | claimed |
| US-20150133543-A1 | TOPICAL GEL COMPOSITION COMPRISING AN INGENOL DERIVATIVE AND A SOLVENT MIXTURE | LEO LABORATORIES LIMITED (IE) | 2015-05-14 | — | — | US | claimed |
| EP-2858629-A1 | A TOPICAL GEL COMPOSITION COMPRISING AN INGENOL DERIVATIVE AND A SOLVENT MIXTURE | Leo Laboratories Limited (IE) | 2015-04-15 | — | — | EP | claimed |
| US-20140350120-A1 | TOPICAL COMPOSITION COMPRISING AN INGENOL DERIVATIVE AND AN OILY SOLVENT | LEO LABORATORIES LIMITED (IE) | 2014-11-27 | — | — | US | claimed |
| US-20140343141-A1 | TOPICAL COMPOSITION COMPRISING AN INGENOL DERIVATIVE AND A SURFACTANT-COSOLVENT MIXTURE | LEO LABORATORIES LIMITED (IE) | 2014-11-20 | — | — | US | claimed |
| EP-2790669-A1 | A TOPICAL COMPOSITION COMPRISING AN INGENOL DERIVATIVE AND AN OILY SOLVENT | LEO LABORATORIES LIMITED (IE) | 2014-10-22 | — | — | EP | claimed |
| EP-2790694-A1 | A TOPICAL COMPOSITION COMPRISING AN INGENOL DERIVATIVE AND A SURFACTANT-COSOLVENT MIXTURE | LEO LABORATORIES LIMITED (IE) | 2014-10-22 | — | — | EP | claimed |
| WO-2014128564-A2 | PHARMACEUTICAL COMPOSITIONS OF CETP INHIBITORS | DR. REDDY'S LABORATORIES LTD. (IN) | 2014-08-28 | — | — | WO | claimed |
| EP-0124274-A2 | Electron beam sensitive mixture resist | GAF CORPORATION (US) | 1984-11-07 | — | — | EP | claimed |
| US-4460385-A | Process for the removal of acid gases from hydrocarbon gases containing the same | EXXON RESEARCH AND ENGINEERING CO. (US) | 1984-07-17 | — | — | US | claimed |
| US-4448876-A | Electron beam sensitive resist | GAF CORPORATION (US) | 1984-05-15 | — | — | US | claimed |
| US-4448875-A | HALF-ESTER OR -AMIDE OF ALKYL VINYL ETHER-MALEIC ANHYDRIDE COPOLYMER | GAF CORPORATION (US) | 1984-05-15 | — | — | US | claimed |
| EP-0037603-B1 | METHOD FOR THE PREPARATION OF N-METHYL OR N-ETHYL-2-PYRROLIDONE | STAMICARBON B.V. (NL) | 1984-02-15 | — | — | EP | claimed |
| EP-0088977-A2 | Electron beam sensitive resist | GAF CORPORATION (US) | 1983-09-21 | — | — | EP | claimed |
| US-4404391-A | Method for the preparation of N-methyl and -N-ethyl-1-pyrrolidones | STAMICARBON B.V. (NL) | 1983-09-13 | — | — | US | claimed |
| EP-0084714-A1 | Ink composition for ink jet printing | KONICA CORPORATION (JP) | 1983-08-03 | — | — | EP | claimed |
| US-4375398-A | CROSSLINKING, VINYL ETHER | GAF CORPORATION (US) | 1983-03-01 | — | — | US | claimed |
| EP-0037603-A1 | Method for the preparation of N-methyl or N-ethyl-2-pyrrolidone | STAMICARBON B.V. (NL) | 1981-10-14 | — | — | EP | claimed |