Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL398275 | 0.76 | ACE (0.54) | ACEMMEPOLBCYP2D6CYP2C9 | |
| SCHEMBL9148349 | 0.73 | ACE (0.51) | ACEMMEPOLBCYP2D6CYP2C9 | |
| SCHEMBL9151384 | 0.71 | ACE (0.49) | ACEMME | |
| SCHEMBL9789660 | 0.71 | ACE (0.61) | ACEMMEPOLBCYP2D6CYP2C9 | |
| SCHEMBL9789659 | 0.71 | ACE (0.61) | ACEMMEPOLBCYP2D6CYP2C9 | |
| SCHEMBL9789687 | 0.71 | ACE (0.61) | ACEMMEPOLBCYP2D6CYP2C9 | |
| SCHEMBL385463 | 0.69 | ACE (0.59) | ACEMMEPOLBCYP2D6CYP2C9 | |
| SCHEMBL6141057 | 0.69 | ACE (0.59) | ACEMMEPOLBCYP2D6CYP2C9 | |
| SCHEMBL385403 | 0.69 | ACE (0.59) | ACEMMEPOLBCYP2D6CYP2C9 | |
| SCHEMBL10371338 | 0.69 | ACE (0.64) | ACEMMEPOLBCYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519877-B1 | 3-Acylamino-2-pyrrolidinones as enhancers of the processes of learning and memory and pharmaceutical compositions containing same | SIGMA TAU IND FARMACEUTI (IT) | 1995-09-27 | — | — | EP | disclosed |