SCHEMBL9286173

SCHEMBL9286173

C#Cc1cccc2ccc(C(=O)O)nc12

nearest known ligand 0.60

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.60
KMT2A Q03164 2/20 0.60
MMP2 P08253 4/20 0.49
MGAM O43451 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
ACMSD Q8TDX5 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MEN1 O00255 1/20 0.44
LMNA P02545 1/20 0.44
PIM1 P11309 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5704347 0.83 KDM4E (0.60) KDM4EKMT2AMMP2MGAMALOX15
SCHEMBL4579443 0.80 CCNC (0.45) KDM4EKMT2AMMP2MGAMALOX15
Benzene SCHEMBL27872024 0.78 KDM4E (0.70) KDM4EKMT2AMMP2MGAMALOX15
SCHEMBL1725005 0.77 KDM4E (0.66) KDM4EKMT2AMMP2MGAMALOX15
Benzene SCHEMBL27888317 0.76 KDM4E (0.68) KDM4EKMT2AMMP2MGAMALOX15
SCHEMBL1088781 0.75 KDM4E (0.67) KDM4EKMT2AMMP2MGAMALOX15
SCHEMBL30170409 0.75 KDM4E (0.68) KDM4EKMT2AMMP2MGAMALOX15
SCHEMBL29697210 0.75 KDM4E (1.00) KDM4EKMT2AMMP2MGAMALOX15
SCHEMBL171491 0.75 KDM4E (1.00) KDM4EKMT2AMMP2MGAMALOX15
SCHEMBL7143621 0.75 KDM4E (0.68) KDM4EKMT2AMMP2MGAMALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5468742-A Antibacterial agents, feed additives BAYER AKTIENGESELLSCHAFT (DE) 1995-11-21 US disclosed