Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL42656 | 0.96 | ALDH1A1 (0.64) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| Boric Acid SCHEMBL28025581 | 0.89 | ALDH1A1 (0.58) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| Hydroquinone SCHEMBL6942759 | 0.88 | ALDH1A1 (0.56) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| Butylated Hydroxytoluene SCHEMBL8504323 | 0.88 | ALDH1A1 (0.72) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| Propene SCHEMBL11271448 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| SCHEMBL8523997 | 0.85 | ALDH1A1 (0.50) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| SCHEMBL10822034 | 0.84 | HSPA5 (0.66) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| SCHEMBL1785592 | 0.83 | CYP2C9 (0.59) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| SCHEMBL31193211 | 0.83 | CYP2C9 (0.59) | ALDH1A1TSHRLMNAMAPK1KMT2A | |
| Phenol SCHEMBL3365396 | 0.83 | GAA (0.54) | ALDH1A1TSHRLMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471120-B1 | Lubricant composition containing phenolic/phosphorodithioate borates as multifunctional additives | MOBIL OIL CORP (US) | 1995-02-15 | — | — | EP | claimed |