SCHEMBL8523997

SCHEMBL8523997

CC(C)(C)c1cc(CO)cc(C(C)(C)C)c1O.CCCCc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
GAA P10253 5/20 0.50
MAPK1 P28482 4/20 0.50
TSHR P16473 4/20 0.50
LMNA P02545 4/20 0.50
KMT2A Q03164 3/20 0.50
NPSR1 Q6W5P4 3/20 0.50
CYP3A4 P08684 3/20 0.50
MEN1 O00255 2/20 0.50
CYP1A2 P05177 2/20 0.50
BLM P54132 2/20 0.50
ATM Q13315 2/20 0.50
HIF1A Q16665 2/20 0.50
ALOX15 P16050 2/20 0.50
GMNN O75496 1/20 0.50
GABBR2 O75899 1/20 0.50
TP53 P04637 1/20 0.50
CYP2C9 P11712 1/20 0.50
NFKB1 P19838 1/20 0.50
CYP2C19 P33261 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39321 0.93 GAA (0.55) ALDH1A1GAAMAPK1TSHRLMNA
Butylated Hydroxytoluene SCHEMBL28067514 0.90 ALDH1A1 (0.50) ALDH1A1GAAMAPK1TSHRLMNA
SCHEMBL23650047 0.89 GAA (0.53) ALDH1A1GAAMAPK1TSHRLMNA
SCHEMBL3343753 0.89 PTGS2 (0.55) ALDH1A1GAAMAPK1TSHRLMNA
SCHEMBL28262122 0.89 ALDH1A1 (0.51) ALDH1A1GAAMAPK1TSHRLMNA
SCHEMBL2201965 0.88 HSPA5 (0.59) ALDH1A1GAAMAPK1TSHRLMNA
SCHEMBL421864 0.87 PTGS2 (0.57) ALDH1A1GAAMAPK1TSHRLMNA
SCHEMBL423476 0.86 PTGS2 (0.58) ALDH1A1GAAMAPK1TSHRLMNA
SCHEMBL222426 0.86 PTGS2 (0.58) ALDH1A1GAAMAPK1TSHRLMNA
SCHEMBL225812 0.86 PTGS2 (0.58) ALDH1A1GAAMAPK1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5866671-A ACETAL RESIN, HYDANTOIN OR IMIDAZOLE DERIVATIVE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-02 US disclosed
US-5043388-A Mixing vulcanizable rubber, fiber forming polyamide, and alkylphenol-formaldehyde resole; controlled temperature extrusion UBE INDUSTRIES, INC. (JP) 1991-08-27 US disclosed
US-4703086-A MIXING A RUBBER, FIBER FORMING POLYAMIDE AND ALKYLPHENOL-FORMALDEHYDE RESOLE UBE INDUSTRIES, LTD. (JP) 1987-10-27 US disclosed