Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570244 | 0.73 | — | — | |
| SCHEMBL10468274 | 0.70 | ROCK2 (0.37) | — | |
| SCHEMBL9080959 | 0.69 | — | — | |
| SCHEMBL10468266 | 0.69 | — | — | |
| SCHEMBL16670900 | 0.68 | — | — | |
| SCHEMBL10467592 | 0.67 | POLB (0.33) | — | |
| SCHEMBL10467385 | 0.66 | — | — | |
| SCHEMBL19579757 | 0.66 | KDM4E (0.43) | HCAR2 | |
| SCHEMBL9276651 | 0.63 | SIRT2 (0.35) | HCAR2 | |
| SCHEMBL119640 | 0.62 | TDP1 (0.44) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0688217-A4 | — | — | 1996-01-10 | — | — | EP | disclosed |
| EP-0688217-A1 | HETEROCYCLE-CONTAINING MACROCYCLIC IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1995-12-27 | — | — | EP | disclosed |