⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10468266 | 0.75 | — | — | |
| SCHEMBL16670900 | 0.73 | — | — | |
| SCHEMBL9286289 | 0.73 | HCAR2 (0.33) | — | |
| SCHEMBL10467385 | 0.71 | — | — | |
| SCHEMBL8531906 | 0.67 | — | — | |
| SCHEMBL5551815 | 0.66 | NISCH (0.37) | — | |
| SCHEMBL242787 | 0.64 | ALDH1A1 (0.48) | — | |
| SCHEMBL9171831 | 0.62 | ALDH1A1 (0.47) | — | |
| Benzotriazole SCHEMBL29754639 | 0.61 | ALDH1A1 (0.33) | — | |
| Benzotriazole SCHEMBL28954700 | 0.60 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3193941-A1 | PRODRUGS COMPRISING AN AMINOALKYL GLYCINE LINKER | Ascendis Pharma A/S (DK) | 2017-07-26 | — | — | EP | claimed |
| US-9695189-B2 | Chemical crosslinkers and compositions thereof | Nguyen, Mark Quang (US) | 2017-07-04 | — | — | US | claimed |
| US-20160143937-A1 | METHODS OF USING CLEAVABLE DRUG CONJUGATES AND COMPOSITIONS THEREOF | Nguyen, Mark Quang (US) | 2016-05-26 | — | — | US | claimed |
| US-9295731-B2 | Cleavable drug conjugates, compositions thereof and methods of use | Nguyen, Mark Quang (US) | 2016-03-29 | — | — | US | claimed |
| WO-2016020373-A1 | PRODRUGS COMPRISING AN AMINOALKYL GLYCINE LINKER | ASCENDIS PHARMA A/S (DK) | 2016-02-11 | — | — | WO | claimed |
| US-20140294851-A1 | CLEAVABLE DRUG CONJUGATES, COMPOSITIONS THEREOF AND METHODS OF USE | Nguyen, Mark Quang (US) | 2014-10-02 | — | — | US | claimed |
| US-20140249319-A1 | CHEMICAL CROSSLINKERS AND COMPOSITIONS THEREOF | Nguyen, Mark Quang (US) | 2014-09-04 | — | — | US | claimed |
| WO-2006066258-A2 | LIPOCONJUGATION OF PEPTIDES | NEOSE TECHNOLOGIES, INC. (US) | 2006-06-22 | — | — | WO | claimed |
| EP-0609899-A1 | Derivatives of amino-ascorbic acid,the processes for their preparation and use | PLIVA FARMACEUTSKA KEMIJSKA PREHRAMBENA I KOZMETICKA INDUSTRIJA DIONICKO DRUSTVO ZAGREB (HR) | 1994-08-10 | — | — | EP | claimed |
| US-4089868-A | Sulfonium salt substantive sunscreen materials | COLGATE-PALMOLIVE COMPANY (US) | 1978-05-16 | — | — | US | claimed |
| US-4022829-A | INTERMEDIATES FOR SUNSCREEN AGENTS | COLGATE-PALMOLIVE COMPANY (US) | 1977-05-10 | — | — | US | claimed |
| EP-3864068-A2 | METHOD OF MAKING RELEASABLE POLYMERIC REAGENTS | Nektar Therapeutics (US) | 2021-08-18 | — | — | EP | disclosed |
| US-10898503-B2 | Cleavable drug conjugates, compositions thereof and methods of use | Nguyen, Mark Quang (US) | 2021-01-26 | — | — | US | disclosed |
| US-9708370-B2 | Azapeptides as CD36 binding compounds | VALORISATION-RECHERCHE, LIMITED PARTNERSHIP (CA) | 2017-07-18 | — | — | US | disclosed |
| US-9695189-B2 | Chemical crosslinkers and compositions thereof | Nguyen, Mark Quang (US) | 2017-07-04 | — | — | US | disclosed |
| EP-0429611-A1 | AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS | Roche Diagnostics GmbH (DE) | 1991-06-05 | — | — | EP | disclosed |
| WO-1990015798-A1 | AMINOALKYL MALEIMIDES AND HAPTENE AND ANTIGEN DERIVATIVES THEREOF AND CONJUGATES WITH PEPTIDES OR PROTEINS | BOEHRINGER MANNHEIM GMBH (DE) | 1990-12-27 | — | — | WO | disclosed |
| WO-1990010718-A1 | SEQUENCING NUCLEIC ACIDS USING CHEMILUMINESCENT DETECTION | MILLIPORE CORPORATION (US) | 1990-09-20 | — | — | WO | disclosed |
| US-4888385-A | BENZOTRIAZOLYLOXYTRIS/DIMETHYLAMINO/PHOSPHONIUM HEXAFLUOROPHOSPHATE AND HYDROXYBENZOTRIAZOLE ACTIVATOR | MILLIPORE CORPORATION (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0289353-A2 | Modified BOP reagent for solid phase peptide synthesis | MILLIPORE CORPORATION (US) | 1988-11-02 | — | — | EP | disclosed |