Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9288106 | 1.00 | MAOA (0.36) | MAOAMAOBCYP2D6MAPK14OPRD1 | |
| SCHEMBL9103204 | 0.90 | CHRM2 (0.39) | MAOAMAOB | |
| SCHEMBL9102725 | 0.90 | CHRM2 (0.41) | — | |
| SCHEMBL9103197 | 0.90 | CHRM2 (0.39) | MAOAMAOB | |
| SCHEMBL9102709 | 0.90 | CHRM2 (0.41) | — | |
| SCHEMBL9100697 | 0.86 | HRH3 (0.39) | OPRK1 | |
| SCHEMBL9103026 | 0.86 | HRH3 (0.39) | OPRK1 | |
| SCHEMBL9100703 | 0.86 | HRH3 (0.39) | OPRK1 | |
| SCHEMBL9886367 | 0.85 | DRD4 (0.37) | MAOAMAOB | |
| SCHEMBL9099364 | 0.85 | HDAC4 (0.37) | HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012074469-A1 | NEW IKACH BLOCKERS | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | WO | disclosed |