Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | PRTN3 | P24158 | 3/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164455 | 0.82 | ELANE (0.38) | ELANEPTGS2POLBKMT2ACALM1 | |
| SCHEMBL13446246 | 0.73 | ELANE (0.39) | ELANEPTGS2POLBKMT2ACALM1 | |
| SCHEMBL14680932 | 0.72 | ELANE (0.48) | ELANEALDH1A1 | |
| SCHEMBL9925703 | 0.71 | ELANE (0.64) | ELANE | |
| SCHEMBL31052 | 0.71 | ALDH1A1 (0.58) | PTGS2CALM1GABRA1GABRG2GABRB3 | |
| SCHEMBL18556937 | 0.70 | ELANE (0.71) | ELANEPRTN3 | |
| SCHEMBL5159822 | 0.70 | ELANE (0.37) | ELANEPOLBPRTN3 | |
| SCHEMBL20306461 | 0.69 | ELANE (0.51) | ELANEPTGS2CALM1PRTN3ALDH1A1 | |
| SCHEMBL15395812 | 0.68 | BACE1 (0.44) | ELANEPTGS2POLBKMT2ACALM1 | |
| Phosphonic Acid SCHEMBL9638832 | 0.68 | ELANE (0.45) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649417-A1 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES | TROPIX, INC. (US) | 1995-04-26 | — | — | EP | disclosed |
| EP-0649417-A4 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES. | TROPIX INC (US) | 1995-02-27 | — | — | EP | disclosed |
| WO-1994026726-A1 | IMPROVED CHEMILUMINESCENT 1,2-DIOXETANES | TROPIX, INC. (US) | 1994-11-24 | — | — | WO | disclosed |