Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 3/20 | 0.60 |
| ▸ | PNP | P00491 | 7/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4384740 | 0.83 | XDH (0.67) | XDHPNPGPR84 | |
| SCHEMBL7809880 | 0.81 | XDH (0.61) | XDHGPR84 | |
| SCHEMBL9288451 | 0.80 | XDH (0.47) | XDHPNPGPR84 | |
| SCHEMBL8522269 | 0.77 | PNP (0.56) | PNPGPR84 | |
| SCHEMBL4128821 | 0.77 | XDH (0.56) | XDHGPR84 | |
| SCHEMBL7777164 | 0.75 | PNP (0.54) | PNPGPR84 | |
| SCHEMBL8536005 | 0.75 | PNP (0.54) | PNPGPR84 | |
| SCHEMBL6272296 | 0.75 | PNP (0.54) | PNPGPR84 | |
| SCHEMBL249649 | 0.75 | XDH (1.00) | XDH | |
| SCHEMBL6272728 | 0.75 | PNP (0.58) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5476659-A | Killing; particularly lymphocytic leukemia | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-12-19 | — | — | US | disclosed |
| WO-1994011003-A1 | CANCEROUS B CELL TREATMENT USING SUBSTITUTED NUCLEOSIDE DERIVATIVES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-05-26 | — | — | WO | disclosed |
| US-4746651-A | ANTIBIOTIC AND ALDOGYCOSIDYL-GUANINE OR ISOXANTHOPTERIN IMMUNE RESPONSE-ENHANCING AGENT | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1988-05-24 | — | — | US | disclosed |