SCHEMBL9288573

SCHEMBL9288573

CC(C)(C)c1ccc(-n2c(-c3ccc(-n4c5ccccc5c5cc(-c6cccc7c6sc6ccccc67)ccc54)cc3)nc3ccccc32)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.40
PTGER4 P35408 2/20 0.38
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
GRIA1 P42261 1/20 0.38
CACNG8 Q8WXS5 1/20 0.38
CACNG2 Q9Y698 1/20 0.38
ALDH1A1 P00352 3/20 0.37
MAPT P10636 1/20 0.37
MAPK1 P28482 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TNKS O95271 1/20 0.37
TNKS2 Q9H2K2 1/20 0.37
TNF P01375 1/20 0.36
NOD1 Q9Y239 1/20 0.36
PTGS2 P35354 1/20 0.35
AKT1 P31749 1/20 0.35
AKT2 P31751 1/20 0.35
AKT3 Q9Y243 1/20 0.35
PPARG P37231 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9288321 0.95 PTGER4 (0.40) ALOX5PTGER4ESR1ESR2GRIA1
SCHEMBL9288593 0.95 ESR1 (0.39) ALOX5PTGER4ESR1ESR2GRIA1
SCHEMBL9290087 0.93 PTGER4 (0.43) ALOX5PTGER4ESR1ESR2GRIA1
SCHEMBL12567859 0.93 ESR1 (0.42) ALOX5ESR1ESR2GRIA1CACNG8
SCHEMBL9288643 0.92 PTGER4 (0.39) ALOX5PTGER4ESR1ESR2GRIA1
SCHEMBL9290146 0.92 ALOX5 (0.42) ALOX5PTGER4ESR1ESR2GRIA1
SCHEMBL458325 0.92 ESR1 (0.44) ALOX5PTGER4ESR1ESR2GRIA1
SCHEMBL15481549 0.92 ESR2 (0.46) ALOX5PTGER4ESR1ESR2GRIA1
SCHEMBL12567988 0.91 ESR2 (0.41) ALOX5PTGER4ESR1ESR2GRIA1
SCHEMBL15481550 0.91 ESR2 (0.46) ALOX5PTGER4ESR1ESR2GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120133274-A1 Carbazole Compound, Light-Emitting Element Material, Organic Semiconductor Material, Light-Emitting Element, Light-Emitting Device, Lighting Device, and Electronic Device BRI3BP, BRD7, CDYL ALOX5 1378/4885PTGER4 1970/4885ESR1 685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.