Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22528225 | 0.87 | PTGS2 (0.55) | TYRPTGS2CYP3A4 | |
| SCHEMBL28127638 | 0.81 | PTGS2 (0.35) | TYRPTGS2CYP3A4GPR84NPC1 | |
| SCHEMBL10235676 | 0.80 | LPL (0.47) | GRIN2DGRIN2AGRIN2BGRIN2CNPC1 | |
| SCHEMBL560468 | 0.79 | CYP2D6 (0.49) | HPGDMAPK1 | |
| SCHEMBL10472566 | 0.79 | CYP2D6 (0.49) | HPGDMAPK1 | |
| SCHEMBL2571201 | 0.79 | CYP2D6 (0.49) | HPGDMAPK1 | |
| SCHEMBL9123014 | 0.79 | GRIN2D (0.46) | PTGS2CYP3A4GPR84GRIN2DGRIN2A | |
| SCHEMBL2314999 | 0.79 | PTGS2 (0.60) | TYRPTGS2CYP3A4 | |
| SCHEMBL16448430 | 0.79 | PTGS2 (0.60) | TYRPTGS2CYP3A4 | |
| SCHEMBL12242288 | 0.79 | GAA (0.48) | TYRCYP3A4HPGDMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300698-A | Process for the prepartion of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | claimed |
| US-5438142-A | Tris(hydroxyphenyl)ethanes having ketone, bromine, sulfonate, or amine groups as condensation polymer modifiers; photostabilizers, flame retardants, discoloration inhibitors, antisoilants, antioxidants | HOECHST CELANESE CORP. (US) | 1995-08-01 | — | — | US | disclosed |
| US-5344980-A | Process for the preparation of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORP. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5344980-A | Process for the preparation of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORP. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5300698-A | Process for the prepartion of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-5300698-A | Process for the prepartion of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-5300559-A | Tris/p-hydroxyphenyl/benzene ether alkyleneoxy amine or modified polyethers; chemical intermediates | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| WO-1993014065-A1 | PROCESS FOR PREPARING 1,3,5- TRIS(4'-HYDROXYPHENYL)BENZENE AND ITS DERIVATIVES | HOECHST CELANESE CORPORATION (US) | 1993-07-22 | — | — | WO | disclosed |
| WO-1993014053-A1 | PROCESS FOR THE PREPARATION OF 1,3,5-TRIS(4'-HYDROXYARYL)BENZENE | HOECHST CELANESE CORPORATION (US) | 1993-07-22 | — | — | WO | disclosed |