Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16189800 | 0.87 | DNM1 (0.38) | TSHRALDH1A1CNR1CNR2HPGD | |
| SCHEMBL30977012 | 0.82 | TSHR (0.46) | TSHRALDH1A1CNR1CNR2MEN1 | |
| SCHEMBL10791875 | 0.82 | TSHR (0.33) | TSHRALDH1A1HPGDDNM1PLA2G2C | |
| SCHEMBL16311935 | 0.80 | TSHR (0.34) | TSHR | |
| SCHEMBL4130405 | 0.79 | CNR1 (0.44) | TSHRALDH1A1CNR1CNR2MEN1 | |
| SCHEMBL12599352 | 0.79 | TSHR (0.43) | TSHRALDH1A1CNR1CNR2MEN1 | |
| SCHEMBL37441 | 0.79 | TSHR (0.43) | TSHRALDH1A1CNR1CNR2MEN1 | |
| SCHEMBL9296230 | 0.79 | MEN1 (0.43) | TSHRALDH1A1CNR1CNR2MEN1 | |
| SCHEMBL30977038 | 0.79 | TSHR (0.43) | TSHRALDH1A1CNR1CNR2MEN1 | |
| SCHEMBL13239248 | 0.79 | TSHR (0.36) | TSHRALDH1A1CNR1CNR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589359-B1 | Process for the production of ketene acetals | WACKER CHEMIE GMBH (DE) | 1995-06-28 | — | — | EP | claimed |
| US-9452426-B2 | Polymer adsorbent | NIPPON FILCON CO., LIMITED (JP) | 2016-09-27 | — | — | US | disclosed |
| EP-2808080-A1 | POLYMER ADSORBENT | Nippon Filcon Co., Ltd. (JP) | 2014-12-03 | — | — | EP | disclosed |
| US-20140332714-A1 | POLYMER ADSORBENT | NIPPON FILCON CO., LIMITED (JP) | 2014-11-13 | — | — | US | disclosed |