Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | ENTPD5 | O75356 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | UGT2B7 | P16662 | 4/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759448 | 1.00 | PTPN1 (0.41) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL20154502 | 1.00 | PTPN1 (0.41) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL16984793 | 0.91 | PTPN1 (0.40) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL16984862 | 0.91 | PTPN1 (0.40) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL16984747 | 0.91 | PTPN1 (0.40) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL19849758 | 0.90 | PTPN1 (0.39) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL6681167 | 0.77 | — | — | |
| SCHEMBL23789999 | 0.72 | ALDH1A1 (0.38) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL19844090 | 0.71 | CYP19A1 (0.39) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL3222541 | 0.71 | ALDH1A1 (0.37) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8759043-B2 | Biocatalytic production of ambroxan | BASF SE (DE) | 2014-06-24 | — | — | US | disclosed |
| US-8759043-B2 | Biocatalytic production of ambroxan | BASF SE (DE) | 2014-06-24 | — | — | US | disclosed |
| US-20120135477-A1 | Biocatalytic Production of Ambroxan | BASF SE (DE) | 2012-05-31 | — | — | US | disclosed |
| US-20120135477-A1 | Biocatalytic Production of Ambroxan | BASF SE (DE) | 2012-05-31 | — | — | US | disclosed |