Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | ENTPD5 | O75356 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | UGT2B7 | P16662 | 4/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL759448 | 1.00 | PTPN1 (0.41) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL9289567 | 1.00 | PTPN1 (0.41) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL16984793 | 0.91 | PTPN1 (0.40) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL16984862 | 0.91 | PTPN1 (0.40) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL16984747 | 0.91 | PTPN1 (0.40) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL19849758 | 0.90 | PTPN1 (0.39) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL6681167 | 0.77 | — | — | |
| SCHEMBL23789999 | 0.72 | ALDH1A1 (0.38) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL19844090 | 0.71 | CYP19A1 (0.39) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR | |
| SCHEMBL3222541 | 0.71 | ALDH1A1 (0.37) | PTPN1ALDH1A1CYP3A4CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10294211-B2 | Process for isolating and purifying ambrox | GIVAUDAN S.A. (CH) | 2019-05-21 | — | — | US | disclosed |
| US-20180134678-A1 | PROCESS FOR ISOLATING AND PURIFYING AMBROX | GIVAUDAN SA (CH) | 2018-05-17 | — | — | US | disclosed |
| US-9248187-B2 | Oxadiazole inhibitors of leukotriene production for combination therapy | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2016-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10294211-B2 | Process for isolating and purifying ambrox | BTD, TPO, MMP13 | PTPN1 4339/4885ALDH1A1 1847/4885CYP3A4 135/4885 |
| US-20180134678-A1 | PROCESS FOR ISOLATING AND PURIFYING AMBROX | BTD, TPO, MMP13 | PTPN1 4339/4885ALDH1A1 1847/4885CYP3A4 135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.