Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 7/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
| ▸ | TGM1 | P22735 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1795535 | 0.86 | HCRTR1 (0.42) | HCRTR1HCRTR2 | |
| SCHEMBL929833 | 0.84 | CHRNB2 (0.49) | GRIN2BF13A1TGM2TGM1CYP2C9 | |
| SCHEMBL654606 | 0.78 | CHRNB2 (0.47) | F13A1TGM2TGM1ALDH1A1HPGD | |
| SCHEMBL649574 | 0.78 | CHRNB2 (0.47) | F13A1TGM2TGM1ALDH1A1HPGD | |
| Fumaric Acid SCHEMBL929017 | 0.77 | HRH3 (0.38) | HCRTR1HCRTR2ALDH1A1HPGDMEN1 | |
| Fumaric Acid SCHEMBL929018 | 0.77 | HRH3 (0.38) | HCRTR1HCRTR2ALDH1A1HPGDMEN1 | |
| Fumaric Acid SCHEMBL929016 | 0.77 | HRH3 (0.38) | HCRTR1HCRTR2ALDH1A1HPGDMEN1 | |
| SCHEMBL930264 | 0.77 | HRH3 (0.44) | HCRTR1HCRTR2 | |
| SCHEMBL3295704 | 0.75 | KDM4E (0.45) | GRIN2BF13A1TGM2TGM1CYP2C9 | |
| SCHEMBL654459 | 0.75 | CHRNB2 (0.45) | GRIN2BF13A1TGM2TGM1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7872010-B2 | Substituted diazabicycloalkane derivatives having affinity for nicotinic acetylcholine receptors | ABBOTT LABORATORIES (US) | 2011-01-18 | — | — | US | disclosed |