SCHEMBL9290285

SCHEMBL9290285

O=C1c2cccc3cccc(c23)N1c1cc(Cl)cc(Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.61
KMT2A Q03164 4/20 0.58
MEN1 O00255 3/20 0.58
ALDH1A1 P00352 4/20 0.47
HPGD P15428 4/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
KDM4E B2RXH2 2/20 0.47
CASP1 P29466 1/20 0.47
MPI P34949 1/20 0.47
CACNA1B Q00975 1/20 0.47
APBA1 Q02410 1/20 0.47
GAA P10253 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.44
TSHR P16473 1/20 0.44
LMNA P02545 1/20 0.44
UBE2N P61088 1/20 0.44
ATM Q13315 1/20 0.44
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10869116 0.84 PDE6D (0.81) PDE6DKMT2AMEN1ALDH1A1HPGD
SCHEMBL9290287 0.81 PDE6D (0.82) PDE6DKMT2AMEN1ALDH1A1HPGD
SCHEMBL9290446 0.79 PDE6D (0.56) PDE6DKMT2AMEN1ALDH1A1HPGD
SCHEMBL10864719 0.78 PDE6D (0.58) PDE6DKMT2AMEN1ALDH1A1HPGD
SCHEMBL9290288 0.77 ALDH1A1 (0.79) PDE6DKMT2AMEN1ALDH1A1HPGD
SCHEMBL11616740 0.75 MEN1 (0.70) KMT2AMEN1ALDH1A1SMN1; SMN2KDM4E
SCHEMBL5535555 0.75 KMT2A (0.60) PDE6DKMT2AMEN1ALDH1A1HPGD
SCHEMBL30553977 0.75 KMT2A (0.70) PDE6DKMT2AMEN1ALDH1A1HPGD
SCHEMBL28283363 0.75 KMT2A (0.70) PDE6DKMT2AMEN1ALDH1A1HPGD
SCHEMBL9290289 0.74 PDE6D (0.65) PDE6DKMT2AMEN1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 PDE6D 69/4885KMT2A 4130/4885MEN1 3537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.