SCHEMBL9290289

SCHEMBL9290289

O=C1c2cccc3cccc(c23)N1c1ccc(C(F)(F)F)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.65
HTR1A P08908 2/20 0.53
DRD2 P14416 2/20 0.53
HTR2A P28223 2/20 0.53
HTR7 P34969 2/20 0.53
HTR6 P50406 2/20 0.53
ALDH1A1 P00352 3/20 0.51
HPGD P15428 3/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
KDM4E B2RXH2 1/20 0.51
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
RXFP1 Q9HBX9 1/20 0.48
GALR3 O60755 1/20 0.47
HTR4 Q13639 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10869116 0.87 PDE6D (0.81) PDE6DALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL9290446 0.87 PDE6D (0.56) PDE6DHTR1ADRD2HTR2AHTR7
SCHEMBL12561287 0.83 PDE6D (0.46) PDE6DHTR1ADRD2HTR2AHTR7
SCHEMBL9290306 0.82 PDE6D (0.45) PDE6DHTR1ADRD2HTR2AHTR7
SCHEMBL9290287 0.81 PDE6D (0.82) PDE6DALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL9290288 0.80 ALDH1A1 (0.79) PDE6DALDH1A1HPGDSMN1; SMN2KDM4E
SCHEMBL9290416 0.80 PDE6D (0.48) PDE6DHTR1ADRD2HTR2AHTR7
SCHEMBL12601309 0.79 PDE6D (0.41) PDE6DHTR1ADRD2HTR2AHTR7
SCHEMBL9290299 0.78 PDE6D (0.40) PDE6DHTR1ADRD2HTR2AHTR7
SCHEMBL9290378 0.78 PDE6D (0.52) PDE6DALDH1A1SMN1; SMN2KDM4EL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 PDE6D 69/4885HTR1A 1107/4885DRD2 675/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.