SCHEMBL9290362

SCHEMBL9290362

CN(C)c1ccc2c3cccc4c(-c5ccc6c7c(cccc57)C(=O)N6C)ccc(c5cccc1c52)c43

nearest known ligand 0.70

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.70
KMT2A Q03164 4/20 0.70
POLB P06746 1/20 0.70
PKM P14618 1/20 0.54
USP2 O75604 3/20 0.53
BRD4 O60885 11/20 0.53
KEAP1 Q14145 2/20 0.43
NFE2L2 Q16236 2/20 0.43
ATM Q13315 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
PRMT1 Q99873 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5578410 0.92 MEN1 (0.77) MEN1KMT2APOLBPKMUSP2
SCHEMBL9290441 0.83 PKM (0.52) MEN1KMT2APOLBPKMUSP2
SCHEMBL11484431 0.83 KMT2A (1.00) MEN1KMT2APOLBPKMUSP2
SCHEMBL9290420 0.76 BRD4 (0.55) MEN1KMT2APOLBPKMUSP2
SCHEMBL12869518 0.75 KMT2A (0.63) MEN1KMT2APOLBPKMUSP2
SCHEMBL12869514 0.75 KMT2A (0.57) MEN1KMT2APOLBPKMUSP2
SCHEMBL9290415 0.75 BRD4 (0.58) MEN1KMT2APOLBPKMUSP2
SCHEMBL9290433 0.74 POLB (0.51) MEN1KMT2APOLBPKMBRD4
SCHEMBL15398140 0.73 BRD4 (0.53) MEN1KMT2APOLBPKMUSP2
SCHEMBL18020496 0.73 TERT (0.47) MEN1KMT2APOLBPKMUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed