SCHEMBL9290442

SCHEMBL9290442

COc1ccc(N2C(=O)c3cccc4cccc2c34)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.65
KMT2A Q03164 4/20 0.62
MEN1 O00255 3/20 0.57
ALDH1A1 P00352 4/20 0.55
KDM4E B2RXH2 3/20 0.55
HTR1A P08908 2/20 0.54
DRD2 P14416 2/20 0.54
HTR2A P28223 2/20 0.54
HTR6 P50406 2/20 0.54
HTR7 P34969 1/20 0.54
NR1H3 Q13133 1/20 0.54
PGR P06401 1/20 0.50
HPGD P15428 3/20 0.48
MAPT P10636 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
RXFP1 Q9HBX9 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
SMN1; SMN2 Q16637 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30553978 0.89 KMT2A (0.75) KMT2AMEN1ALDH1A1KDM4EHTR1A
SCHEMBL28283366 0.89 KMT2A (0.75) KMT2AMEN1ALDH1A1KDM4EHTR1A
SCHEMBL10869116 0.87 PDE6D (0.81) PDE6DKMT2AMEN1ALDH1A1KDM4E
SCHEMBL9290288 0.83 ALDH1A1 (0.79) PDE6DKMT2AMEN1ALDH1A1KDM4E
SCHEMBL12561290 0.83 KMT2A (0.60) PDE6DKMT2AMEN1ALDH1A1KDM4E
SCHEMBL9290294 0.82 KMT2A (0.59) PDE6DKMT2AMEN1ALDH1A1KDM4E
SCHEMBL9290287 0.81 PDE6D (0.82) PDE6DKMT2AMEN1ALDH1A1KDM4E
SCHEMBL9290476 0.80 KMT2A (0.55) PDE6DKMT2AMEN1ALDH1A1KDM4E
SCHEMBL7647376 0.79 KMT2A (0.58) KMT2AMEN1ALDH1A1KDM4EHTR1A
SCHEMBL12600949 0.79 KMT2A (0.44) PDE6DKMT2AMEN1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2695930-B1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE, NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE DAINIPPON INK & CHEMICALS (JP) 2019-09-11 EP disclosed
US-9475991-B2 Polymerizable liquid crystal composition, polarized light-emitting coating material, novel naphtholactam derivative novel coumarin derivative, novel nile red derivative, and novel anthracene derivative ADEKA CORPORATION (JP) 2016-10-25 US disclosed
US-9475991-B2 Polymerizable liquid crystal composition, polarized light-emitting coating material, novel naphtholactam derivative novel coumarin derivative, novel nile red derivative, and novel anthracene derivative ADEKA CORPORATION (JP) 2016-10-25 US disclosed
US-20130334461-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE ADEKA CORPORATION (JP) 2013-12-19 US disclosed
US-20130334461-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLARIZED LIGHT-EMITTING COATING MATERIAL, NOVEL NAPHTHOLACTAM DERIVATIVE NOVEL COUMARIN DERIVATIVE, NOVEL NILE RED DERIVATIVE, AND NOVEL ANTHRACENE DERIVATIVE ADEKA CORPORATION (JP) 2013-12-19 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
US-8350054-B2 Optical filter ADEKA CORPORATION (JP) 2013-01-08 US disclosed
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed
US-20110152538-A1 OPTICAL FILTER ADEKA CORPORATION (JP) 2011-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110152538-A1 OPTICAL FILTER C1R, CBR3, CBR1 PDE6D 69/4885KMT2A 4130/4885MEN1 3537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.