SCHEMBL9290294

SCHEMBL9290294

C=Cc1cc2c3c(cccc3c1)C(=O)N2c1ccc(OC)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.59
NR1H3 Q13133 3/20 0.45
PDE6D O43924 1/20 0.45
HTR1A P08908 2/20 0.44
DRD2 P14416 2/20 0.44
HTR2A P28223 2/20 0.44
HTR6 P50406 2/20 0.44
HTR7 P34969 1/20 0.44
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 3/20 0.43
PGR P06401 1/20 0.43
MEN1 O00255 2/20 0.42
ESR1 P03372 1/20 0.42
CASP3 P42574 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
NR1H2 P55055 1/20 0.41
MAPT P10636 1/20 0.40
BRD1 O95696 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12561290 0.89 KMT2A (0.60) KMT2ANR1H3PDE6DHTR1ADRD2
SCHEMBL9290293 0.85 PDE6D (0.55) KMT2APDE6DKDM4EALDH1A1MEN1
SCHEMBL9290442 0.82 PDE6D (0.65) KMT2ANR1H3PDE6DHTR1ADRD2
SCHEMBL9290298 0.81 PDE6D (0.44) KMT2APDE6DKDM4EALDH1A1MEN1
SCHEMBL9290306 0.81 PDE6D (0.45) KMT2ANR1H3PDE6DHTR1ADRD2
SCHEMBL9290364 0.80 PDE6D (0.50) KMT2APDE6DKDM4EALDH1A1MEN1
SCHEMBL30553978 0.78 KMT2A (0.75) KMT2ANR1H3HTR1ADRD2HTR2A
SCHEMBL28283366 0.78 KMT2A (0.75) KMT2ANR1H3HTR1ADRD2HTR2A
SCHEMBL12561292 0.76 PDE6D (0.41) KMT2APDE6DKDM4EALDH1A1MEN1
SCHEMBL12561289 0.73 PDE6D (0.56) KMT2APDE6DKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2458941-A1 OPTICAL FILTER Adeka Corporation (JP) 2012-05-30 EP disclosed