Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9290952 | 0.84 | ALDH1A1 (0.47) | TDP1ATMNPSR1KDM4EALDH1A1 | |
| SCHEMBL9291073 | 0.81 | MAPT (0.47) | TDP1NPSR1ALDH1A1GAAMEN1 | |
| SCHEMBL16046169 | 0.80 | POLB (0.40) | NPSR1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL28225367 | 0.79 | NPSR1 (0.45) | NPSR1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL27670207 | 0.76 | TDP1 (0.55) | TDP1ATMNPSR1KDM4EALDH1A1 | |
| SCHEMBL12379209 | 0.74 | ATM (0.53) | TDP1ATMNPSR1KDM4EALDH1A1 | |
| SCHEMBL1205809 | 0.72 | TDP1 (0.57) | TDP1ATMNPSR1KDM4EALDH1A1 | |
| SCHEMBL10774513 | 0.71 | SMN1; SMN2 (0.40) | ATMNPSR1ALDH1A1GAAMEN1 | |
| SCHEMBL1205811 | 0.71 | TDP1 (0.56) | TDP1ATMNPSR1KDM4EALDH1A1 | |
| SCHEMBL1791077 | 0.71 | TDP1 (0.55) | TDP1ATMNPSR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334760-A | Reacting a dichlorophosphine compound with acrylic acid or methacrylic acid in presence of a peroxide or an azo catalysts then hydration | SAKAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |