Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291069 | 0.84 | TDP1 (0.44) | ALDH1A1KDM4EGAATDP1ATM | |
| SCHEMBL12379209 | 0.80 | ATM (0.53) | ALDH1A1KDM4EGAATDP1ATM | |
| SCHEMBL9290956 | 0.79 | MAPT (0.50) | ALDH1A1GAATDP1CFTRNPSR1 | |
| SCHEMBL27670207 | 0.79 | TDP1 (0.55) | ALDH1A1KDM4EGAATDP1ATM | |
| SCHEMBL4558544 | 0.75 | CFTR (0.60) | ALDH1A1KDM4ECFTRPOLBMEN1 | |
| SCHEMBL1205809 | 0.75 | TDP1 (0.57) | ALDH1A1KDM4EGAATDP1ATM | |
| SCHEMBL1205811 | 0.74 | TDP1 (0.56) | ALDH1A1KDM4EGAATDP1ATM | |
| SCHEMBL1791077 | 0.74 | TDP1 (0.55) | ALDH1A1KDM4EGAATDP1ATM | |
| SCHEMBL30201392 | 0.74 | TDP1 (0.55) | ALDH1A1KDM4EGAATDP1ATM | |
| SCHEMBL8606909 | 0.73 | ALDH1A1 (0.55) | ALDH1A1CFTRNPSR1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5334760-A | Reacting a dichlorophosphine compound with acrylic acid or methacrylic acid in presence of a peroxide or an azo catalysts then hydration | SAKAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-02 | — | — | US | disclosed |