SCHEMBL929121

SCHEMBL929121

CCOc1ccc(C(=O)Cl)c(C(=O)O)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.51
SMN1; SMN2 Q16637 5/20 0.51
ALDH1A1 P00352 3/20 0.51
HPGD P15428 2/20 0.51
CYP1A2 P05177 1/20 0.51
TSHR P16473 1/20 0.51
HSD17B10 Q99714 1/20 0.51
NOTUM Q6P988 1/20 0.46
PLA2G4B P0C869 1/20 0.45
MAPT P10636 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
PRKAB2 O43741 1/20 0.44
PRKAG1 P54619 1/20 0.44
PRKAA2 P54646 1/20 0.44
PRKAA1 Q13131 1/20 0.44
PRKAG3 Q9UGI9 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL930228 0.90 ALDH1A1 (0.59) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL27923255 0.83 KDM4E (0.68) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL28274069 0.82 TDP1 (0.51) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL28275887 0.81 KDM4E (0.53) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL4729840 0.81 KDM4E (0.57) KDM4EALDH1A1HPGDTSHRHSD17B10
SCHEMBL15935983 0.81 TAS1R3 (0.54) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL5032922 0.81 KDM4E (0.53) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL4844621 0.81 KDM4E (0.70) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL4649271 0.80 KDM4E (0.51) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2
SCHEMBL8677505 0.79 KDM4E (0.54) KDM4ESMN1; SMN2ALDH1A1HPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8753790-B2 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS, LLC (US) 2014-06-17 US disclosed
EP-2448991-B1 A SELF-IMAGEABLE FILM FORMING POLYMER, COMPOSITIONS THEREOF AND DEVICES AND STRUCTURES MADE THEREFROM PROMERUS LLC (US) 2014-02-26 EP disclosed
EP-2448991-A2 A SELF-IMAGEABLE FILM FORMING POLYMER, COMPOSITIONS THEREOF AND DEVICES AND STRUCTURES MADE THEREFROM Promerus, LLC (US) 2012-05-09 EP disclosed
US-20110104614-A1 Self-imageable film forming polymer, compositions thereof and devices and structures made therefrom PROMERUS LLC 2011-05-05 US disclosed
WO-2011002516-A2 A SELF-IMAGEABLE FILM FORMING POLYMER, COMPOSITIONS THEREOF AND DEVICES AND STRUCTURES MADE THEREFROM PROMERUS LLC (US) 2011-01-06 WO disclosed