Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 6/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291146 | 1.00 | SPHK1 (0.36) | SPHK1PTPN11FPR2S1PR3HTR2A | |
| SCHEMBL9291441 | 1.00 | SPHK1 (0.36) | SPHK1PTPN11FPR2S1PR3HTR2A | |
| SCHEMBL9291460 | 1.00 | SPHK1 (0.36) | SPHK1PTPN11FPR2S1PR3HTR2A | |
| SCHEMBL9291806 | 1.00 | SPHK1 (0.36) | SPHK1PTPN11FPR2S1PR3HTR2A | |
| SCHEMBL9291372 | 0.99 | FPR2 (0.34) | SPHK1PTPN11FPR2 | |
| SCHEMBL9291245 | 0.96 | PDE4A (0.34) | SPHK1FPR2 | |
| SCHEMBL9291443 | 0.93 | FPR2 (0.37) | FPR2HTR2AHTR2CHTR2B | |
| SCHEMBL16638902 | 0.89 | SPHK1 (0.37) | SPHK1PTPN11FPR2 | |
| SCHEMBL19985313 | 0.89 | SPHK1 (0.37) | SPHK1PTPN11FPR2 | |
| SCHEMBL19985314 | 0.89 | SPHK1 (0.37) | SPHK1PTPN11FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356563-A | Two plate electrooptical cell | HOFFMANN-LA ROCHE INC. (US) | 1994-10-18 | — | — | US | disclosed |
| US-5244597-A | Liquid crystalline mixtures having a chiral tilted smectic phase | HOFFMANN-LA ROCHE INC. (US) | 1993-09-14 | — | — | US | disclosed |